About 7 results found for searched term "CD73-IN-2" (0.14 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M21256 | CD73-IN-2 | Others |
| CD73-IN-2 is a potent CD73 inhibitor with an IC50 of 0.09 nM. | ||
| M9910 | CDKI-73 | CDK |
| CDKI73; Asnuciclib; LS-007 | ||
| Cdki-73 (LS-007) is an orally active and highly effective CDK9 inhibitor with Ki values of 4 nM, 4 nM and 3 nM against CDK9, CDK1 and CDK2, respectively. Cdki-73 down-regulates phosphorylation of RNA polymerase II. Cdki-73 is also an inhibitor of Rab11. | ||
| M10869 | OP-5244 | Others |
| OP-5244 is a potent and orally active CD73 inhibitor,IC50 The value is 0.25 nM. OP-5244 reverses the immunosuppressive effect by blocking the production of adenosine, with the potential to conduct cancer research. | ||
| M11275 | PSB-12379 | Others |
| Psb-12379 is a nucleotide analogue and a potent ECTO-5 '-nucleotidase (CD73) inhibitor with Kis values of 9.03 nM (rat) and 2.21 nM (human). | ||
| M29608 | MRS4620 | Immunology/Inflammation |
| MRS4620 is a potent CD73 inhibitor, with a Ki of 0.436 nM. MRS4620 can be use for the research of cancer immunoresearch. | ||
| M41259 | CDD-1733 | Anti-infection |
| CDD-1733 is a non-covalent and non-peptide potent SARS-CoV-2 Mpro inhibitor with a Ki of 12 nM. | ||
| M43397 | Leniolisib phosphate | PI3K |
| Leniolisib (CDZ173) phosphate is a first-in-class, potent and selective PI3Kδ inhibitor with an IC50 value of 11 nM.Leniolisib is more selective for PI3K-δ than PI3K-α (28-fold), PI3K-β (43-fold) and PI3K-γ (257-fold). -γ (257-fold). In a cellular assay, Leniolisib decreased pAKT pathway activity and inhibited the proliferation and activation of B and T cell subsets. | ||
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